Biswendu B Goswami
FDA Center for Food Safety and Applied Nutrition (Retired), USA
Title: Virus identification: Development of methods in the post-PCR antiviral therapy
Biography
Biography: Biswendu B Goswami
Abstract
The necessity for rapid methods of virus identification arose from the fact that human diseases caused by viruses range from self-limiting to deadly infections. Each of these virus species have dozens of genotypes. The number of human infections reported each year has made viruses a major public health problem world-wide. Food-borne viruses in particular, are causing more and more localized epidemics that are very difficult to trace and identify, and have been associated with high morbidity and increasingly high mortality. Currently, other than common disinfection guidelines and a few synthetic antivirals, there are no effective control measures available. Development of immunologic protocols remain time consuming and expensive. Detection of viruses are mostly being done by PCR or immunological detection in blood or other body fluids. However, current available PCR methods are inadequate to identify the virus strain and emergence of new genotypes that may no longer be controlled by an established active or passive immunotherapeutic protocol agent. Here we deal with molecular techniques to circumvent these obstacles.