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11th Annual Biomarkers and Clinical Research Congress, will be organized around the theme “Lab to Industry as Biomarkers to Therapeutic Discovery”

Biomarkers 2019 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Biomarkers 2019

Submit your abstract to any of the mentioned tracks.

Register now for the conference by choosing an appropriate package suitable to you.

Biomarker is a key molecular or cellular event that links a specific environmental exposure to a health outcome. Biomarkers can be all that can be appropriately measured as an indicator of normal biological working, pathogenic paths or a drug response to a therapeutic drug intervention. Biomarkers play a dynamic role in accepting the relationships between exposure to environmental chemicals, the development of chronic human diseases, and the identification of subgroups that are at increased risk for disease. Biomarkers are used in many specific fields.

  • Medicine
  • Regulatory validation
  •  Cell biology
  • Geology and astrobiology
  • Ecotoxicology
  • Track 1-1Lipid biomarkers
  • Track 1-2Cardiovascular biomarkers
  • Track 1-3Neurological biomarkers
  • Track 1-4Pathological biomarkers
  • Track 1-5New strategies for discovery

Biomarker discovery requires sure identification of a biomarker with real-time quantitative information to indicate proteins which are altering to a statistically applicable degree in response to disease. The discovery of biomarkers has been developed a new strategies from the initial stages. In the first stage of biomarker discovery proceedings, investigation depends upon mass spectrometry techniques to make unbiased, semiquantitative analysis of changes between healthy and diseased conditions. The slope of probable biomarkers generated in the discovery stage is to be further substantiated due to the high false positive rate. It is done through more targeted and quantitative mass spectrometry techniques, such as immuno-affinity peptide enrichment.

This track includes, the latest trends in discovery, development and identification of biomarkers are discussed. There are many new strategies present in development of biomarkers. In this section advancements of biomarkers in various sectors like paediatric diseases biomarkers, clinical biomarkers, and clinical analysis of NGS samples are covered.

  • Track 2-1Protein biomarker discovery
  • Track 2-2Biomarkers for pediatric diseases
  • Track 2-3Clinical biomarker advancements
  • Track 2-4New strategies for discovery
  • Track 2-5Mass spectrometry biomarker discovery

Biomarkers have numerous uses in pharmaceutical R & D. With the present introduction of high-performance composition, protein and gene arrays and bioinformatics, clinical conclusions like Drug development and selecting the type of treatment can be made proficiently. Still, there is an insufficiency of effective biomarkers to increase the drug development from pre-clinical through all levels of clinical studies. Biomarker in Drug Discovery main lead to the advance of Modified Medicines.

  • Track 3-1Biomarker in Drug Design
  • Track 3-2Medicine Development in Oncology and Infectious Diseases
  • Track 3-3Drug discovery innovation and strategies
  • Track 3-4Phenotypic and genomic drug discovery
  • Track 3-5Computational chemistry and informatics for drug discovery

Biomarkers that can regulator several diseases of the immune system such as autoimmunity, immunodeficiency, cancer, allergies and infections are called immunological biomarkers. As the immune system interrelates with all other systems in the body, it theatres a very important role in the discovery of biomarkers. Immunological biomarkers, such as miRNA and serum Biomarkers can deliver info about the immune response of a body under normal or abnormal conditions.

  • Track 4-1Challenges to biomarkers development in Immune system
  • Track 4-2Biomarkers discovery in Immunology
  • Track 4-3Biomarkers for Early Progressive Inflammatory & Immunological Diseases
  • Track 4-4Biomarkers of Disease Pathogenesis
  • Track 4-5Biomarkers under autoimmune system

Biomarkers play a significant role in oncology that is used in clinical research for risk valuation, differential diagnosis, determination of the nature of tumors, for recognition purposes, to determine the prognosis and dose-response of the drug to the cure. The procedure indicative of the presence of cancer in the body is carried out by means of tools known as cancer biomarkers. There are different types of cancer in which biomarkers have their presentation, such as lung, melanoma, breast, colorectal, pancreas and many more. Biochemically, cancer biomarkers can be DNA, RNA, proteins, peptides, hormones, metabolites and even biological procedures such as apoptosis, angiogenesis or proliferation. Around three key types of cancer biomarkers depending on their clinical use: prognostic, predictive and pharmacodynamics markers.

  • Track 5-1Cancer Biomarkers in clinical research
  • Track 5-2Diagnosis and treatment
  • Track 5-3Lung Cancer
  • Track 5-4Cervical Cancer
  • Track 5-5Ovarian Cancer
  • Track 5-6Breast Cancer
  • Track 5-7Prostate cancer
  • Track 5-8Testicular Cancer

The Biomarkers discover is major important application in the field of cancer innovations through Biomarker meetings.  Bioethics is a protected innovation which makes to increase the standard of theory regarding clinical approval of biomarkers. Right now use of biomarkers is blasting business. A large portion of the developed associations like Parexel, pfizer and Quintiles are into clinical innovative work. Different types of reporting bias and publication bias, make the association between CRP and prognosis among patients with stable coronary disease one of the most emerging iinovative work by using prognostic biomarker. Publication bias, statistical analytic protocols and registration of studies are one of other measures which might help increase the quality of prognostic biomarker research.

  • Track 6-1Bioethics
  • Track 6-2Statistical protocols of biomarkers
  • Track 6-3Case studies

A reliable therapeutic biomarker would facilitate the identity of current management algorithms, ensure that pathogenic mechanisms were eliminated prior to treatment withdrawal, and reduce the frequency of unnecessary sustained therapy. Hence there are various researches in progress to discover new biomarkers for various diseases starting from cardiovascular disorders  to  autoimmune disorders and Genetic disorders.Emerging therapeutic biomarkers in Cancers: Endometrial Cancer, Ovarian cancer, Melanoma, Non-small cell lung cancer, Lung Cancer etc.

  • Track 7-1Melanoma
  • Track 7-2Ovarian cancer
  • Track 7-3Endometrial cancer
  • Track 7-4Non-small cell lung cancer

The biomarkers used in treatment of cancer is called as cancer biomarkers. Now a days biomarkers plays a crucial role in cancer prognosis, diagnosis and treatment of cancers. Role of biomarkers in cancer research and medicine are Risk assessment, Diagnosis, Prognosis and treatment predictions, Pharmacodynamics and Pharmacokinetics, Monitoring treatment response and Recurrence. There are different types of cancer biomarkers like Prognostic, Pharmacodynamic, Predictive. The major types of cancers in which biomarkers are widely being used in lung cancer, breast cancer, blood cancer, prostate cancer and colorectal cancer. Cancer biomarkers conferences provide a good platform to enhance discussion on various new researches.

  • Track 8-1Prognostic cancer biomarker
  • Track 8-2Pharmacodynamic cancer biomarker
  • Track 8-3Predictive cancer biomarker
  • Track 8-4Biomarkers for gastric cancer
  • Track 8-5Biomarkers for colorectal cancer
  • Track 8-6Uses of biomarkers in Cancer research

Biomarkers play an important role in prognosis and diagnosis of various cardiovascular and neurological diseases. The diseases which are deadly from ages has a possible treatment and easy diagnosis with the help of advancements in biomarkers through different diagnostics methods and imaging technologies. Cardiac biomarkers and neuro biomarkers has brought a great revolution in disease diagnosis and prognosis. These biomarkers are also used in many other non-cancerous diseases. Some of the important ones are Alzheimer’s disease, cardiovascular diseases, Huntington's disease, Neurodegenerative diseases, Diabetes and Behcet’s disease.

 

  • Track 9-1Biomarkers for Cardiovascular diseases
  • Track 9-2Biomarkers for Neurodegenerative diseases
  • Track 9-3Biomarkers for diabetes
  • Track 9-4Biomarkers for Behcet s disease
  • Track 9-5Biomarkers for Alzheimer
  • Track 9-6Biomarkers for Huntington s disease

Biomarkers plays  particularly  role in the field of 'personalized medicine'. Moreover, they may be helpful in detecting therapeutic and adverse responses and in patient stratification based on efficacy or safety prediction. Thus, biomarkers are essential tools for the selection of appropriate patients for treatment with certain drugs to and enable personalized medicine, that is 'providing the right treatment to the right patient, at the right dose at the right time'. Prognostic biomarkers are of particular significance for malignant conditions. Similarly, Diagnostic biomarkers are important in autoimmune diseases. Disease severity biomarkers are helpful tools in the treatment for inflammatory skin diseases. Identification, qualification and implementation of the different kinds of biomarkers are challenging and frequently necessitate collaborative efforts.

  • Track 10-1Drug development and usage
  • Track 10-2Drug development and usage
  • Track 10-3Metabolic Disorders
  • Track 10-4Genetic disorders
  • Track 10-5DNA biomarkers
  • Track 10-6Immune disorders

The ability to look at a patient individually will provide a more precise cancer diagnosis and specific treatment plan. The genetic information from individuals can then be used to effectively treat them, by finding the variations that can account for possible diseases. An individual’s genetic make-up also plays a large part in their extent of response to a certain treatment, and hence, having the knowledge of their genetic content can alter the type of treatment they receive. These approaches are intended to identify individualized patient benefits of therapies, minimize the risk of toxicity and reduce the cost of treatment.

In personalized medicine, biomarkers have a special place, which mends with cancer diagnosis, drug development and usage and cancer genomics. Challenges in these fields are an interesting topic to be discussed as there are radiant solutions emerging.

  • Track 11-1Diagnostic and prognostic biomarkers
  • Track 11-2Tumor biomarkers
  • Track 11-3Diagnosis and intervention
  • Track 11-4Drug development and usage
  • Track 11-5Cancer Genomics
  • Track 11-6Challenges and probable solutions

In the biomarker pipeline, the technologies that will enable the use of biomarkers in drug discovery and development vary depending on the research stage. The second stage, biomarker validation and clinical assay development, depends upon extremely sensitive and specific high-throughput immunoassays. The single greatest challenge in discovering biomarkers with clinical utility is the sensitivity and specificity necessary to determine that a biomarker is truly positive for disease or disease toxicodynamics, and can be used to detect deviations from normal. The molecular biomarkers conferences provide good exposure in drug discovery. Biomarkers have special applications in the areas of translational medicine, clinical development and safety assessment where they are put through several stages of drug discovery, development and validation.

  • Omics Technologies in Biomarkers Discovery and Validation
  • Latest diagnosis techniques
  • Assessment of drug response
  • Advancements in analysis
  • Application of tools

Biomarkers imaging is a cross-discipline which is an intersection of in vivo imaging and molecular biology. It facilitates the picturing of the cellular function and the supplement of the molecular process in biological processes without disturbing the living organisms. The various fields of study the Biomarkers Imaging brings life into are diagnosis of diseases such as cancer, cardiovascular diseases and neurological disorders. This technique also donates to the improvisation of the treatment of various diseases and disorders by adjusting the pre-clinical and clinical tests of new drugs. The biomarkers dynamics meetings are also expected to have a major economic impact due to very prior and more precise diagnosis.

Biomarkers imaging techniques using biomarkers popularly known as Imaging biomarkers have an important role in screening in various diseases particularly cancer screening using various new generation tools and technologies.