. Sihem Bihorel
Assistant Professor
University of Florida
USA
Biography
Dr. Sihem Bihorel (Ait-Oudhia) is an assistant professor at the Department of Pharmaceutics, University of Florida. Her laboratory is located at the Center for Pharmacometrics and Systems Pharmacology in Lake Nona, Orlando. In her research, Dr. Bihorel utilizes quantitative systems pharmacology approaches to guide the development of new therapies and the identification of promising combination therapies as well as of novel biomarkers in oncology. She integrates quantitative systems pharmacology with PK/PD modeling and simulation to advance drug discovery and development, and leverage the understanding of drugs action which holds great promise to facilitate translational research. Her research is also focused on investigating how priming solid tumors with pro-apoptotic agents enhances the deposition and efficacy of subsequent associated macromolecules and how these combination can be beneficial in defeating drug resistance in cancer. Prior to her current position, Dr. Bihorel was research assistant professor at the department of pharmaceutical sciences at the School of Pharmacy at the University at Buffalo (SUNY Buffalo). She also graduated with a PhD and was postdoctoral associate from the same.
Research Interest
Her research is also focused on investigating how priming solid tumors with pro-apoptotic agents enhances the deposition and efficacy of subsequent associated macromolecules and how these combination can be beneficial in defeating drug resistance in cancer.