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A-Lien Lu-Chang

A-Lien Lu-Chang

University of Maryland Medical School


Dr A-Lien Lu-Chang completed her PhD from University of North Carolina at Chepel Hill and postdoctoral studies from Duke University School of Medicine with Dr. Paul Modrich (Nobel laureate in Chemistry in 2015). She is the Professor of Biochemistry and Molecular Biology at University of Maryland Medical School and a member of University of Maryland Greenebaum Comprehensive Cancer Center. She has published more than 63 peer-reviewed papers in reputed journals, holds a potent, and has been serving as an editorial board members of four journals.

Research Interest

My laboratory is studying the interplays among DNA repair, DNA replication, cell cycle checkpoint, transcription, and chromatin remodeling. We investigate the impact of their coordination on telomere integrity and carcinogensis. Our work highlights potential targets that can be exploited clinically for cancer therapies.