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Paul Tempst


Paul Tempst

Memorial Sloan Kettering Cancer Center, USA

Biography

Paul Tempst, PhD, has 40 years of experience in protein chemistry, biochemistry, molecular biology and mass spectrometry, including as a Postdoc at Caltech, Junior Faculty at Harvard Medical School, and Professor at Memorial Sloan Kettering Cancer Center and at the Weill Graduate School of Cornell University (New York). He leads a proteomics and biomarker discovery team and has collaborated worldwide to identify novel proteins and protein complexes: PDGF, Prions, NFkB, IkB, NF-E2, PI3K, mTOR, Raptor, p27kip, SNAREs, Mediator, Elongator, Polycomb, RSC, SWI/SNF, Exosome, and Histone deacetylases, methylases, demethylases and ubiquitinating complexes. His lab pioneered the evaluation and use of protease activities as biomarkers for cancer.

Abstract

Abstract : Aminopeptidase activities as biomarkers for cancer